Cargando…
Constitutive activation of breast tumor kinase accelerates cell migration and tumor growth in vivo
Breast tumor kinase (BRK) is a non-receptor tyrosine kinase overexpressed in most human breast tumors, including lymph node metastases, but undetected in normal mammary tissue or in fibroadenomas. The activity of BRK-like Src family tyrosine kinase, is regulated negatively by phosphorylation of C-te...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412638/ https://www.ncbi.nlm.nih.gov/pubmed/23552639 http://dx.doi.org/10.1038/oncsis.2012.11 |