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Constitutive activation of breast tumor kinase accelerates cell migration and tumor growth in vivo

Breast tumor kinase (BRK) is a non-receptor tyrosine kinase overexpressed in most human breast tumors, including lymph node metastases, but undetected in normal mammary tissue or in fibroadenomas. The activity of BRK-like Src family tyrosine kinase, is regulated negatively by phosphorylation of C-te...

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Detalles Bibliográficos
Autores principales: Miah, S, Martin, A, Lukong, K E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412638/
https://www.ncbi.nlm.nih.gov/pubmed/23552639
http://dx.doi.org/10.1038/oncsis.2012.11