CCR7-expressing B16 melanoma cells downregulate interferon-γ-mediated inflammation and increase lymphangiogenesis in the tumor microenvironment

The expression of the CC chemokine receptor-7 (CCR7) by cancers, including melanoma, augments lymph node (LN) metastasis, but little is known about its role in lymphangiogenesis and anti-tumor immunity. We injected control B16 murine melanoma cells (pLNCX2-B16) and CCR7-overexpressing B16 cells (CCR...

Descripción completa

Detalles Bibliográficos
Autores principales: Takekoshi, T, Fang, L, Paragh, G, Hwang, S T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412639/
https://www.ncbi.nlm.nih.gov/pubmed/23552640
http://dx.doi.org/10.1038/oncsis.2012.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412639/
https://www.ncbi.nlm.nih.gov/pubmed/23552640
http://dx.doi.org/10.1038/oncsis.2012.9

Ejemplares similares