miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma

Epithelial-to-mesenchymal transition (EMT) is associated with poor prognosis and metastasis in hepatocellular carcinoma. We have previously demonstrated an in vivo model of liver cancer in which mesenchymal cells post-EMT demonstrate a high rate of invasive growth and metastasis. Here, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, W, Dang, H, You, H, Steinway, S, Takahashi, Y, Wang, H-G, Liao, J, Stiles, B, Albert, R, Rountree, C B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412647/
https://www.ncbi.nlm.nih.gov/pubmed/23552699
http://dx.doi.org/10.1038/oncsis.2012.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412647/
https://www.ncbi.nlm.nih.gov/pubmed/23552699
http://dx.doi.org/10.1038/oncsis.2012.15

Ejemplares similares