Cargando…

miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma

Epithelial-to-mesenchymal transition (EMT) is associated with poor prognosis and metastasis in hepatocellular carcinoma. We have previously demonstrated an in vivo model of liver cancer in which mesenchymal cells post-EMT demonstrate a high rate of invasive growth and metastasis. Here, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, W, Dang, H, You, H, Steinway, S, Takahashi, Y, Wang, H-G, Liao, J, Stiles, B, Albert, R, Rountree, C B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412647/ https://www.ncbi.nlm.nih.gov/pubmed/23552699 http://dx.doi.org/10.1038/oncsis.2012.15

Ejemplares similares

Induction of tumor initiation is dependent on CD44s in c-Met(+) hepatocellular carcinoma
por: Dang, Hien, et al.
Publicado: (2015)

The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met(+) Hepatocellular Carcinoma
por: Steinway, Steven N., et al.
Publicado: (2015)

miR-200b and miR-200c co-contribute to the cisplatin sensitivity of ovarian cancer cells by targeting DNA methyltransferases
por: Liu, Jue, et al.
Publicado: (2019)

MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis
por: Wong, Chun-Ming, et al.
Publicado: (2015)

Mechanisms and Functions of MiR-200 Family in Hepatocellular Carcinoma
por: Mao, Yinqi, et al.
Publicado: (2021)

The Kindlin-2 regulation of epithelial-to-mesenchymal transition in breast cancer metastasis is mediated through miR-200b
por: Sossey-Alaoui, Khalid, et al.
Publicado: (2018)

Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity
por: Pan, Yanchun, et al.
Publicado: (2016)

MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
por: Xue, Xiaofeng, et al.
Publicado: (2014)

LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway
por: Li, Shi-Peng, et al.
Publicado: (2016)

Erratum: Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity
por: Pan, Yanchun, et al.
Publicado: (2016)

miR-200b Inhibits Prostate Cancer EMT, Growth and Metastasis
por: Williams, LaTanya V., et al.
Publicado: (2013)

miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas
por: Tseng, Jill H., et al.
Publicado: (2017)

MiR-195 suppresses the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by inhibiting YAP
por: Yu, Shuo, et al.
Publicado: (2017)

Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition
por: Haraguchi, Takeshi, et al.
Publicado: (2016)

MiR-449a suppresses the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by multiple targets
por: Chen, Shu-peng, et al.
Publicado: (2015)

miR-338-3p inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cells
por: Chen, Jing-Song, et al.
Publicado: (2016)

Mechanism of methyltransferase like 3 in epithelial-mesenchymal transition process, invasion, and metastasis in esophageal cancer
por: Liang, Xuyang, et al.
Publicado: (2021)

Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics
por: Dang, Hien, et al.
Publicado: (2011)

Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model
por: Banyard, Jacqueline, et al.
Publicado: (2013)

Goosecoid Promotes the Metastasis of Hepatocellular Carcinoma by Modulating the Epithelial-Mesenchymal Transition
por: Xue, Tong-Chun, et al.
Publicado: (2014)

BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells
por: Kim, Jeong Seon, et al.
Publicado: (2015)

MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell
por: Lu, Yuhua, et al.
Publicado: (2014)

RESTORATION OF CELL-MEDIATED IMMUNITY TO ANIMALS BLOCKED BY A HUMORAL RESPONSE
por: MacKaness, George B., et al.
Publicado: (1974)

MicroRNA miR-509-3p inhibit metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma
por: Zhang, Huiming, et al.
Publicado: (2021)

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer
por: Meng, Xiaodan, et al.
Publicado: (2016)

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles
por: Bhome, Rahul, et al.
Publicado: (2022)

PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma
por: Chen, Weibo, et al.
Publicado: (2021)

MicroRNA-200a inhibits cell growth and metastasis by targeting Foxa2 in hepatocellular carcinoma
por: Chen, Shu-ying, et al.
Publicado: (2017)

miR‐200c and phospho‐AKT as prognostic factors and mediators of osteosarcoma progression and lung metastasis
por: Berlanga, Pablo, et al.
Publicado: (2016)

miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition
por: Sulaiman, Siti A., et al.
Publicado: (2016)

Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells through upregulating mir-200a/b expression via association with p73
por: Lu, Zhenduo, et al.
Publicado: (2015)

miR-10a restores human mesenchymal stem cell differentiation by repressing KLF4
por: Li, Jiao, et al.
Publicado: (2013)

miR-205 and miR-200c: Predictive Micro RNAs for Lymph Node Metastasis in Triple Negative Breast Cancer
por: Berber, Ufuk, et al.
Publicado: (2014)

Expression of human miR-200b-3p and -200c-3p in cytomegalovirus-infected tissues
por: Lee, Kyoung Hwa, et al.
Publicado: (2018)

Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels
por: Lee, Yang-ja, et al.
Publicado: (2018)

Circulating microRNA-200 Family as Diagnostic Marker in Hepatocellular Carcinoma
por: Dhayat, Sameer A., et al.
Publicado: (2015)

Asymmetrical methyltransferase PRMT3 regulates human mesenchymal stem cell osteogenesis via miR-3648
por: Min, Zhang, et al.
Publicado: (2019)

Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes
por: Steinway, Steven Nathaniel, et al.
Publicado: (2015)

miR-148a, miR-152 and miR-200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression
por: Gurbuz, Venhar, et al.
Publicado: (2021)

DNA Methyltransferases Modulate Hepatogenic Lineage Plasticity of Mesenchymal Stromal Cells
por: Lee, Chien-Wei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rs2fese4klvdjo5oke55sc7sk7