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A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy

BACKGROUND: At recurrence the use of nitrosoureas is widely-used as a therapeutic option for glioblastoma (GBM) patients. The efficacy of fotemustine (FTM) has been demonstrated in phase II clinical trials; however, these papers report a wide range of progression-free-survival (PFS-6 m) rates, rangi...

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Detalles Bibliográficos
Autores principales: Paccapelo, Alessandro, Lolli, Ivan, Fabrini, Maria Grazia, Silvano, Giovanni, Detti, Beatrice, Perrone, Franco, Savio, Giuseppina, Santoni, Matteo, Bonizzoni, Erminio, Perrone, Tania, Scoccianti, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412703/
https://www.ncbi.nlm.nih.gov/pubmed/22583678
http://dx.doi.org/10.1186/1479-5876-10-90