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Alu expression in human cell lines and their retrotranspositional potential

BACKGROUND: The vast majority of the 1.1 million Alu elements are retrotranspositionally inactive, where only a few loci referred to as ‘source elements’ can generate new Alu insertions. The first step in identifying the active Alu sources is to determine the loci transcribed by RNA polymerase III (...

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Detalles Bibliográficos
Autores principales: Oler, Andrew J, Traina-Dorge, Stephen, Derbes, Rebecca S, Canella, Donatella, Cairns, Brad R, Roy-Engel, Astrid M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412727/
https://www.ncbi.nlm.nih.gov/pubmed/22716230
http://dx.doi.org/10.1186/1759-8753-3-11