Are different stoichiometries feasible for complexes between lymphotoxin-alpha and tumor necrosis factor receptor 1?

BACKGROUND: Tumor necrosis factors, TNF and lymphotoxin-α (LT), are cytokines that bind to two receptors, TNFR1 and TNFR2 (TNF-receptor 1 and 2) to trigger their signaling cascades. The exact mechanism of ligand-induced receptor activation is still unclear. It is generally assumed that three recepto...

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Detalles Bibliográficos
Autores principales: Mascarenhas, Nahren Manuel, Kästner, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412742/
https://www.ncbi.nlm.nih.gov/pubmed/22568977
http://dx.doi.org/10.1186/1472-6807-12-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412742/
https://www.ncbi.nlm.nih.gov/pubmed/22568977
http://dx.doi.org/10.1186/1472-6807-12-8

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