AP-1 Mediated Transcriptional Repression of Matrix Metalloproteinase-9 by Recruitment of Histone Deacetylase 1 in Response to Interferon β

Matrix metalloproteinase-9 (MMP-9) is a 92 kDa zinc-dependant endopeptidase that degrades components of the extracellular matrix. Increased expression of MMP-9 is implicated in many pathological conditions including metastatic cancer, multiple sclerosis, and atherosclerosis. Although it has been wid...

Descripción completa

Detalles Bibliográficos
Autores principales: Mittelstadt, Megan L., Patel, Rekha C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412826/
https://www.ncbi.nlm.nih.gov/pubmed/22879913
http://dx.doi.org/10.1371/journal.pone.0042152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412826/
https://www.ncbi.nlm.nih.gov/pubmed/22879913
http://dx.doi.org/10.1371/journal.pone.0042152

Ejemplares similares