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Selfish Spermatogonial Selection: Evidence from an Immunohistochemical Screen in Testes of Elderly Men

The dominant congenital disorders Apert syndrome, achondroplasia and multiple endocrine neoplasia–caused by specific missense mutations in the FGFR2, FGFR3 and RET proteins respectively–represent classical examples of paternal age-effect mutation, a class that arises at particularly high frequencies...

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Detalles Bibliográficos
Autores principales: Lim, Jasmine, Maher, Geoffrey J., Turner, Gareth D. H., Dudka-Ruszkowska, Wioleta, Taylor, Stephen, Meyts, Ewa Rajpert-De, Goriely, Anne, Wilkie, Andrew O. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412839/
https://www.ncbi.nlm.nih.gov/pubmed/22879958
http://dx.doi.org/10.1371/journal.pone.0042382