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Waking Action of Ursodeoxycholic Acid (UDCA) Involves Histamine and GABA(A) Receptor Block

Since ancient times ursodeoxycholic acid (UDCA), a constituent of bile, is used against gallstone formation and cholestasis. A neuroprotective action of UDCA was demonstrated recently in models of Alzheimer's disease and retinal degeneration. The mechanisms of UDCA action in the nervous system...

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Detalles Bibliográficos
Autores principales: Yanovsky, Yevgenij, Schubring, Stephan R., Yao, Quiaoling, Zhao, Yan, Li, Sha, May, Andrea, Haas, Helmut L., Lin, Jian-Sheng, Sergeeva, Olga A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412845/
https://www.ncbi.nlm.nih.gov/pubmed/22880010
http://dx.doi.org/10.1371/journal.pone.0042512