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Prognostic Impact of FoxP3+ Regulatory T Cells in Relation to CD8+ T Lymphocyte Density in Human Colon Carcinomas

BACKGROUND: T-lymphocyte infiltration into colon carcinomas can influence clinical outcome, and interactions among T cell subsets may be more informative than either subset alone. Our objective was to examine the prognostic impact of tumor-infiltrating FoxP3(+) regulatory T cells (Tregs) in relation...

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Detalles Bibliográficos
Autores principales: Yoon, Harry H., Orrock, Jared M., Foster, Nathan R., Sargent, Daniel J., Smyrk, Thomas C., Sinicrope, Frank A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412852/
https://www.ncbi.nlm.nih.gov/pubmed/22879926
http://dx.doi.org/10.1371/journal.pone.0042274