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Serotonin Potentiates Transforming Growth Factor-beta3 Induced Biomechanical Remodeling in Avian Embryonic Atrioventricular Valves

Embryonic heart valve primordia (cushions) maintain unidirectional blood flow during development despite an increasingly demanding mechanical environment. Recent studies demonstrate that atrioventricular (AV) cushions stiffen over gestation, but the molecular mechanisms of this process are unknown....

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Detalles Bibliográficos
Autores principales: Buskohl, Philip R., Sun, Michelle L., Thompson, Robert P., Butcher, Jonathan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412853/
https://www.ncbi.nlm.nih.gov/pubmed/22880017
http://dx.doi.org/10.1371/journal.pone.0042527