Genomic Aberrations in an African American Colorectal Cancer Cohort Reveals a MSI-Specific Profile and Chromosome X Amplification in Male Patients

OBJECTIVE: DNA aberrations that cause colorectal cancer (CRC) occur in multiple steps that involve microsatellite instability (MSI) and chromosomal instability (CIN). Herein, we studied CRCs from AA patients for their CIN and MSI status. EXPERIMENTAL DESIGN: Array CGH was performed on 30 AA colon tu...

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Detalles Bibliográficos
Autores principales: Brim, Hassan, Lee, Edward, Abu-Asab, Mones S., Chaouchi, Mohamed, Razjouyan, Hadi, Namin, Hassanzadeh, Goel, Ajay, Schäffer, Alejandro A., Ashktorab, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412863/
https://www.ncbi.nlm.nih.gov/pubmed/22879877
http://dx.doi.org/10.1371/journal.pone.0040392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412863/
https://www.ncbi.nlm.nih.gov/pubmed/22879877
http://dx.doi.org/10.1371/journal.pone.0040392

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