Cargando…

Genomic Aberrations in an African American Colorectal Cancer Cohort Reveals a MSI-Specific Profile and Chromosome X Amplification in Male Patients

OBJECTIVE: DNA aberrations that cause colorectal cancer (CRC) occur in multiple steps that involve microsatellite instability (MSI) and chromosomal instability (CIN). Herein, we studied CRCs from AA patients for their CIN and MSI status. EXPERIMENTAL DESIGN: Array CGH was performed on 30 AA colon tu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brim, Hassan, Lee, Edward, Abu-Asab, Mones S., Chaouchi, Mohamed, Razjouyan, Hadi, Namin, Hassanzadeh, Goel, Ajay, Schäffer, Alejandro A., Ashktorab, Hassan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412863/ https://www.ncbi.nlm.nih.gov/pubmed/22879877 http://dx.doi.org/10.1371/journal.pone.0040392

Ejemplares similares

An Integrative CGH, MSI and Candidate Genes Methylation Analysis of Colorectal Tumors
por: Brim, Hassan, et al.
Publicado: (2014)

Role of life events in the presence of colon polyps among African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2013)

BMI and the risk of colorectal adenoma in African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2014)

Gastric Helicobacter pylori infection associates with an increased risk of colorectal polyps in African Americans
por: Brim, Hassan, et al.
Publicado: (2014)

Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics?
por: Ahmad, Sami, et al.
Publicado: (2022)

A meta-analysis of MSI frequency and race in colorectal cancer
por: Ashktorab, Hassan, et al.
Publicado: (2016)

Predictors of Mortality in Hospitalized African American Covid-19 Cancer Patients
por: Challa, Suryanarayana Reddy, et al.
Publicado: (2022)

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia
por: Ashktorab, Hassan, et al.
Publicado: (2017)

Fr093 COVID-19 PEDIATRIC PATIENTS IN THE UNITED STATES; AFRICAN AMERICAN AND HISPANIC AMONG MOST HOSPITALIZED PATIENTS WITH PERSISTENT GI MANIFESTATIONS
por: Ashktorab, Yusuf, et al.
Publicado: (2021)

Atrial Fibrillation and Colonic Neoplasia in African Americans
por: Nouraie, Mehdi, et al.
Publicado: (2015)

Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia
por: Brim, Hassan, et al.
Publicado: (2018)

Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions
por: Shokrani, Babak, et al.
Publicado: (2020)

Obesity and Pancreatic Cysts in African American Patients
por: Shahnazi, Anahita, et al.
Publicado: (2018)

Lymph nodes’ evaluation in relation to colorectal cancer staging among African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2015)

Determination of distinctive hypomethylated genes in African American colorectal neoplastic lesions
por: Ashktorab, Hassan, et al.
Publicado: (2020)

Case-Control Study of Vitamin D, dickkopf homolog 1 (DKK1) Gene Methylation, VDR Gene Polymorphism and the Risk of Colon Adenoma in African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2011)

Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia
por: Ashktorab, Hassan, et al.
Publicado: (2019)

Exploring the Incidence and Associated Risk Factors of Barrett’s Esophagus in African Americans: A Retrospective Study
por: Ashktorab, Hassan, et al.
Publicado: (2023)

Elevated Liver Enzymes, Ferritin, C-reactive Protein, D-dimer, and Age Are Predictive Markers of Outcomes Among African American and Hispanic Patients With Coronavirus Disease 2019
por: Ashktorab, Hassan, et al.
Publicado: (2021)

Microbiome Analysis of Stool Samples from African Americans with Colon Polyps
por: Brim, Hassan, et al.
Publicado: (2013)

Editorial to the Special Issue ‘Nutritional Intervention in Digestive Diseases in the Era of Nutraceuticals, Nutrigenomics and Microbiomics’
por: Ashktorab, Hassan, et al.
Publicado: (2023)

Reduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2016)

Gastrointestinal manifestations and SARS-CoV-2 infection
por: Pizuorno, Antonio, et al.
Publicado: (2021)

Saffron, Its Active Components, and Their Association with DNA and Histone Modification: A Narrative Review of Current Knowledge
por: Rashid, Mudasir, et al.
Publicado: (2022)

Adiponectin, Leptin, IGF-1, and Tumor Necrosis Factor Alpha As Potential Serum Biomarkers for Non-Invasive Diagnosis of Colorectal Adenoma in African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2018)

Distinct Genetic Alterations in Colorectal Cancer
por: Ashktorab, Hassan, et al.
Publicado: (2010)

Can the rate and location of sessile serrated polyps be part of colorectal Cancer disparity in African Americans?
por: Nouraie, Mehdi, et al.
Publicado: (2019)

SLC5A8 Gene, A Transporter of Butyrate: A Gut Flora Metabolite, Is Frequently Methylated in African American Colon Adenomas
por: Brim, Hassan, et al.
Publicado: (2011)

Endometriosis Gene Expression Heterogeneity and Biosignature: A Phylogenetic Analysis
por: Abu-Asab, Mones, et al.
Publicado: (2011)

Algorithmic Assessment of Vaccine-Induced Selective Pressure and Its Implications on Future Vaccine Candidates
por: Abu-Asab, Mones S., et al.
Publicado: (2010)

COVID-19 Pediatric Patients: Gastrointestinal Symptoms, Presentations, and Disparities by Race/Ethnicity in a Large, Multicenter US Study
por: Ashktorab, Yusuf, et al.
Publicado: (2021)

Pediatric COVID-19 and Gastrointestinal Symptoms in Africa
por: Brim, Anas, et al.
Publicado: (2021)

Systems Biology Profiling of AMD on the Basis of Gene Expression
por: Abu-Asab, Mones S., et al.
Publicado: (2013)

COVID-19 in Latin America: Symptoms, Morbidities, and Gastrointestinal Manifestations
por: Ashktorab, Hassan, et al.
Publicado: (2021)

Inflammation and Cell Death in Age-Related Macular Degeneration: An Immunopathological and Ultrastructural Model
por: Ardeljan, Christopher P., et al.
Publicado: (2014)

Astrocytoma and IDH1-Wildtype Glioblastoma (GBM) Cells Colonize Tumor Vessels and Deploy Vascular Mimicry
por: Maraqah, Haitham H., et al.
Publicado: (2023)

A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation
por: Brim, Hassan, et al.
Publicado: (2017)

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer
por: Ashktorab, Hassan, et al.
Publicado: (2016)

Colorectal Carcinogenesis: MSI-H Versus MSI-L
por: Pawlik, Timothy M., et al.
Publicado: (2004)

Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk
por: Ashktorab, Hassan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_33rf7kjfqtgvn3kc842f4jf6kf