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A rapid method for combined analysis of common and rare variants at the level of a region, gene, or pathway
Previously described methods for the combined analysis of common and rare variants have disadvantages such as requiring an arbitrary classification of variants or permutation testing to assess statistical significance. Here we propose a novel method which implements a weighting scheme based on allel...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413013/ https://www.ncbi.nlm.nih.gov/pubmed/22888262 http://dx.doi.org/10.2147/AABC.S33049 |