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Hypoxia decreases podocyte expression of slit diaphragm proteins

BACKGROUND: Chronic hypoxia contributes to progressive tubulointerstitial injury and, consequently, renal failure. However, the effect of hypoxia on glomerular podocytes, which are integral to the slit diaphragm complex and responsible for selectivity of the glomerular filtration barrier, has not be...

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Detalles Bibliográficos
Autores principales: Lu, Hong, Kapur, Gaurav, Mattoo, Tej K, Lyman, William D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413038/
https://www.ncbi.nlm.nih.gov/pubmed/22888268
http://dx.doi.org/10.2147/IJNRD.S27332