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Argonaute identity defines the length of mature mammalian microRNAs

MicroRNAs (miRNAs) are 19- to 25-nt-long non-coding RNAs that regulate gene expression by base-pairing with target mRNAs and reducing their stability or translational efficiency. Mammalian miRNAs function in association with four closely related Argonaute proteins, AGO1–4. All four proteins contain...

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Detalles Bibliográficos
Autores principales: Juvvuna, Prasanna Kumar, Khandelia, Piyush, Lee, Li Ming, Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413106/
https://www.ncbi.nlm.nih.gov/pubmed/22505576
http://dx.doi.org/10.1093/nar/gks293