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Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers

The transcription factor Sox2 is essential for neural stem cells (NSC) maintenance in the hippocampus and in vitro. The transcription factor Emx2 is also critical for hippocampal development and NSC self-renewal. Searching for ‘modifier’ genes affecting the Sox2 deficiency phenotype in mouse, we obs...

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Detalles Bibliográficos
Autores principales: Mariani, J., Favaro, R., Lancini, C., Vaccari, G., Ferri, A. L., Bertolini, J., Tonoli, D., Latorre, E., Caccia, R., Ronchi, A., Ottolenghi, S., Miyagi, S., Okuda, A., Zappavigna, V., Nicolis, S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413107/
https://www.ncbi.nlm.nih.gov/pubmed/22495934
http://dx.doi.org/10.1093/nar/gks295