Cargando…

Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers

The transcription factor Sox2 is essential for neural stem cells (NSC) maintenance in the hippocampus and in vitro. The transcription factor Emx2 is also critical for hippocampal development and NSC self-renewal. Searching for ‘modifier’ genes affecting the Sox2 deficiency phenotype in mouse, we obs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mariani, J., Favaro, R., Lancini, C., Vaccari, G., Ferri, A. L., Bertolini, J., Tonoli, D., Latorre, E., Caccia, R., Ronchi, A., Ottolenghi, S., Miyagi, S., Okuda, A., Zappavigna, V., Nicolis, S. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413107/ https://www.ncbi.nlm.nih.gov/pubmed/22495934 http://dx.doi.org/10.1093/nar/gks295

Ejemplares similares

A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells
por: Cantu', Claudio, et al.
Publicado: (2011)

The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis
por: Liu, Chia-Feng, et al.
Publicado: (2015)

The transcription factor Sox5 modulates Sox10 function during melanocyte development
por: Stolt, C. Claus, et al.
Publicado: (2008)

SOX9 reprograms endothelial cells by altering the chromatin landscape
por: Fuglerud, Bettina M, et al.
Publicado: (2022)

Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve
por: Srinivasan, Rajini, et al.
Publicado: (2012)

Evaluation of the determinants for improved pluripotency induction and maintenance by engineered SOX17
por: Hu, Haoqing, et al.
Publicado: (2023)

BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation
por: Marathe, Himangi G., et al.
Publicado: (2017)

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity
por: McCann, Alex J, et al.
Publicado: (2021)

Myrf guides target gene selection of transcription factor Sox10 during oligodendroglial development
por: Aprato, Jessica, et al.
Publicado: (2020)

The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template
por: Coustry, Françoise, et al.
Publicado: (2010)

Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer
por: Küspert, Melanie, et al.
Publicado: (2011)

Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells
por: Shi, Zhongcheng, et al.
Publicado: (2015)

Transcription factor Sox10 orchestrates activity of a neural crest-specific enhancer in the vicinity of its gene
por: Wahlbuhl, Mandy, et al.
Publicado: (2012)

The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers
por: Yao, Baojin, et al.
Publicado: (2015)

DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors
por: Narasimhan, Kamesh, et al.
Publicado: (2015)

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures
por: Rahmoun, Massilva, et al.
Publicado: (2017)

KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
por: Bernhardt, Celine, et al.
Publicado: (2022)

Engineered zinc-finger transcription factors activate OCT4 (POU5F1), SOX2, KLF4, c-MYC (MYC) and miR302/367
por: Ji, Qingzhou, et al.
Publicado: (2014)

A far-upstream (−70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration
por: Mead, Timothy J., et al.
Publicado: (2013)

HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells
por: Koizume, Shiro, et al.
Publicado: (2012)

Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex
por: Chou, Shen-Ju, et al.
Publicado: (2009)

MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters
por: Okuda, Hiroshi, et al.
Publicado: (2014)

Non-coding murine centromeric transcripts associate with and potentiate Aurora B kinase
por: Ferri, Federica, et al.
Publicado: (2009)

Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation
por: Lanzafame, Manuela, et al.
Publicado: (2021)

RNA secondary structures regulate three steps of Rho-dependent transcription termination within a bacterial mRNA leader
por: Kriner, Michelle A., et al.
Publicado: (2017)

Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon
por: Fefelova, Elena A, et al.
Publicado: (2022)

CKI isoforms α and ε regulate Star–PAP target messages by controlling Star–PAP poly(A) polymerase activity and phosphoinositide stimulation
por: Laishram, Rakesh S., et al.
Publicado: (2011)

Predicting the strength of UP-elements and full-length E. coli σ(E) promoters
por: Rhodius, Virgil A., et al.
Publicado: (2012)

Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo
por: Johnson, Thomas A, et al.
Publicado: (2018)

Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells
por: Ilyin, Artem A., et al.
Publicado: (2017)

CTCF binds to sites in the major histocompatibility complex that are rapidly reconfigured in response to interferon-gamma
por: Ottaviani, Diego, et al.
Publicado: (2012)

Mechanism of promoter repression by Lac repressor–DNA loops
por: Becker, Nicole A., et al.
Publicado: (2013)

Localized modulation of DNA supercoiling, triggered by the Shigella anti-silencer VirB, is sufficient to relieve H-NS-mediated silencing
por: Picker, Michael A, et al.
Publicado: (2023)

Arabidopsis DNA polymerase ϵ recruits components of Polycomb repressor complex to mediate epigenetic gene silencing
por: del Olmo, Iván, et al.
Publicado: (2016)

Horizontally acquired regulatory gene activates ancestral regulatory system to promote Salmonella virulence
por: Choi, Jeongjoon, et al.
Publicado: (2020)

A polar barrier to transcription can be circumvented by remodeler-induced nucleosome translocation
por: Gaykalova, Daria A., et al.
Publicado: (2011)

Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins
por: Pradeepa, Madapura M., et al.
Publicado: (2014)

The elongation factor Spn1 is a multi-functional chromatin binding protein
por: Li, Sha, et al.
Publicado: (2018)

Regulation of AT1R expression through HuR by insulin
por: Paukku, Kirsi, et al.
Publicado: (2012)

Identification of multiple roles for histone acetyltransferase 1 in replication-coupled chromatin assembly
por: Agudelo Garcia, Paula A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sj7iugu7ogordb1cn1e4vap432