Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens

The utilization of archived, formalin-fixed paraffin-embedded (FFPE) tumor samples for massive parallel sequencing has been challenging due to DNA damage and contamination with normal stroma. Here, we perform whole genome sequencing of DNA isolated from two triple-negative breast cancer tumors archi...

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Detalles Bibliográficos
Autores principales: Yost, Shawn E., Smith, Erin N., Schwab, Richard B., Bao, Lei, Jung, HyunChul, Wang, Xiaoyun, Voest, Emile, Pierce, John P., Messer, Karen, Parker, Barbara A., Harismendy, Olivier, Frazer, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413110/
https://www.ncbi.nlm.nih.gov/pubmed/22492626
http://dx.doi.org/10.1093/nar/gks299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413110/
https://www.ncbi.nlm.nih.gov/pubmed/22492626
http://dx.doi.org/10.1093/nar/gks299

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