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Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve

Myelin is essential for the rapidity of saltatory nerve conduction, and also provides trophic support for axons to prevent axonal degeneration. Two critical determinants of myelination are SOX10 and EGR2/KROX20. SOX10 is required for specification of Schwann cells from neural crest, and is required...

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Detalles Bibliográficos
Autores principales: Srinivasan, Rajini, Sun, Guannan, Keles, Sunduz, Jones, Erin A., Jang, Sung-Wook, Krueger, Courtney, Moran, John J., Svaren, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413122/
https://www.ncbi.nlm.nih.gov/pubmed/22492709
http://dx.doi.org/10.1093/nar/gks313