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Combinatorial targeting of ribbon–helix–helix artificial transcription factors to chimeric recognition sites

Artificial transcription factors (ATFs) are potent synthetic biology tools for modulating endogenous gene expression and precision genome editing. The ribbon–helix–helix (RHH) superfamily of transcription factors are widespread in bacteria and archaea. The principal DNA binding determinant in this f...

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Detalles Bibliográficos
Autores principales: Zampini, Massimiliano, Hayes, Finbarr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413123/
https://www.ncbi.nlm.nih.gov/pubmed/22492712
http://dx.doi.org/10.1093/nar/gks314