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Combinatorial targeting of ribbon–helix–helix artificial transcription factors to chimeric recognition sites
Artificial transcription factors (ATFs) are potent synthetic biology tools for modulating endogenous gene expression and precision genome editing. The ribbon–helix–helix (RHH) superfamily of transcription factors are widespread in bacteria and archaea. The principal DNA binding determinant in this f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413123/ https://www.ncbi.nlm.nih.gov/pubmed/22492712 http://dx.doi.org/10.1093/nar/gks314 |