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DNA origami as biocompatible surface to match single-molecule and ensemble experiments

Single-molecule experiments on immobilized molecules allow unique insights into the dynamics of molecular machines and enzymes as well as their interactions. The immobilization, however, can invoke perturbation to the activity of biomolecules causing incongruities between single molecule and ensembl...

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Detalles Bibliográficos
Autores principales: Gietl, Andreas, Holzmeister, Phil, Grohmann, Dina, Tinnefeld, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413134/
https://www.ncbi.nlm.nih.gov/pubmed/22523083
http://dx.doi.org/10.1093/nar/gks326