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The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage

The Escherichia coli AlkB protein (EcAlkB) is a DNA repair enzyme which reverses methylation damage such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC). The mammalian AlkB homologues ALKBH2 and ALKBH3 display EcAlkB-like repair activity in vitro, but their substrate specificities are differ...

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Detalles Bibliográficos
Autores principales: Meza, Trine J., Moen, Marivi N., Vågbø, Cathrine B., Krokan, Hans E., Klungland, Arne, Grini, Paul E., Falnes, Pål Ø.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413135/
https://www.ncbi.nlm.nih.gov/pubmed/22532610
http://dx.doi.org/10.1093/nar/gks327