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β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3′-UTR and interacts with HuR in colon cancer cells

RNA-binding proteins regulate multiple steps of RNA metabolism through both dynamic and combined binding. In addition to its crucial roles in cell adhesion and Wnt-activated transcription in cancer cells, β-catenin regulates RNA alternative splicing and stability possibly by binding to target RNA in...

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Detalles Bibliográficos
Autores principales: Kim, Inae, Kwak, Hoyun, Lee, Hee Kyu, Hyun, Soonsil, Jeong, Sunjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413138/
https://www.ncbi.nlm.nih.gov/pubmed/22544606
http://dx.doi.org/10.1093/nar/gks331