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TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress

Transcription factor IIS (TFIIS) stimulates RNA cleavage by RNA polymerase II by allowing backtracked enzymes to resume transcription elongation. Yeast cells do not require TFIIS for viability, unless they suffer severe transcriptional stress due to NTP-depleting drugs like 6-azauracil or mycophenol...

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Detalles Bibliográficos
Autores principales: Gómez-Herreros, Fernando, de Miguel-Jiménez, Lola, Morillo-Huesca, Macarena, Delgado-Ramos, Lidia, Muñoz-Centeno, María C., Chávez, Sebastián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413141/
https://www.ncbi.nlm.nih.gov/pubmed/22544605
http://dx.doi.org/10.1093/nar/gks340