Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the σ(A)-containing RNA polymerase holoenzyme

RbpA is an RNA polymerase (RNAP)-binding protein whose presence increases the tolerance levels of Mycobacteria to the first-line anti-tuberculosis drug rifampicin by an unknown mechanism. Here, we show that the role of Mycobacterium tuberculosis RbpA in resistance is indirect because it does not aff...

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Detalles Bibliográficos
Autores principales: Hu, Yangbo, Morichaud, Zakia, Chen, Shiyun, Leonetti, Jean-Paul, Brodolin, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413145/
https://www.ncbi.nlm.nih.gov/pubmed/22570422
http://dx.doi.org/10.1093/nar/gks346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413145/
https://www.ncbi.nlm.nih.gov/pubmed/22570422
http://dx.doi.org/10.1093/nar/gks346

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