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Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the σ(A)-containing RNA polymerase holoenzyme
RbpA is an RNA polymerase (RNAP)-binding protein whose presence increases the tolerance levels of Mycobacteria to the first-line anti-tuberculosis drug rifampicin by an unknown mechanism. Here, we show that the role of Mycobacterium tuberculosis RbpA in resistance is indirect because it does not aff...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413145/ https://www.ncbi.nlm.nih.gov/pubmed/22570422 http://dx.doi.org/10.1093/nar/gks346 |