The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability

Bacteria and yeast possess one RecQ helicase homolog whereas humans contain five RecQ helicases, all of which are important in preserving genome stability. Three of these, BLM, WRN and RECQL4, are mutated in human diseases manifesting in premature aging and cancer. We are interested in determining t...

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Detalles Bibliográficos
Autores principales: Singh, Dharmendra Kumar, Popuri, Venkateswarlu, Kulikowicz, Tomasz, Shevelev, Igor, Ghosh, Avik K., Ramamoorthy, Mahesh, Rossi, Marie L., Janscak, Pavel, Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413146/
https://www.ncbi.nlm.nih.gov/pubmed/22544709
http://dx.doi.org/10.1093/nar/gks349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413146/
https://www.ncbi.nlm.nih.gov/pubmed/22544709
http://dx.doi.org/10.1093/nar/gks349

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