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The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2

Trypanosomatids, such as the sleeping sickness parasite Trypanosoma brucei, contain a ∼20S RNA-editing complex, also called the editosome, which is required for U-insertion/deletion editing of mitochondrial mRNAs. The editosome contains a core of 12 proteins including the large interaction protein A...

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Detalles Bibliográficos
Autores principales: Park, Young-Jun, Budiarto, Tanya, Wu, Meiting, Pardon, Els, Steyaert, Jan, Hol, Wim G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413154/
https://www.ncbi.nlm.nih.gov/pubmed/22561373
http://dx.doi.org/10.1093/nar/gks369