Overexpression of human SOD1 improves survival of mice susceptible to endotoxic shock

BACKGROUND: Protective effects of the antioxidant enzyme Cu-Zn superoxide dismutase (SOD1) against endotoxic shock have not been demonstrated in animal models. We used a murine model to investigate whether overexpression of SOD1 protects against endotoxic shock, and whether the genetic background of...

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Detalles Bibliográficos
Autores principales: Charchaflieh, Jean, Labaze, Georges I, Li, Pulsar, Van Remmen, Holly, Lee, Haekyung, Stutz, Helen, Richardson, Arlan, Emanuel, Asher, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413208/
https://www.ncbi.nlm.nih.gov/pubmed/22879777
http://dx.doi.org/10.2147/JIR.S32073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413208/
https://www.ncbi.nlm.nih.gov/pubmed/22879777
http://dx.doi.org/10.2147/JIR.S32073

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