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Quercetin enhances ABCA1 expression and cholesterol efflux through a p38-dependent pathway in macrophages

ATP-binding cassette transporter A1 (ABCA1) plays a crucial role in exporting cholesterol from macrophages, a function relevant to its involvement in the prevention of atherosclerosis. Quercetin, one of flavonoids, has been described to reduce atherosclerotic lesion formation. This study is aimed to...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Cheng, Lee, Tzong-Shyuan, Chiang, An-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413225/
https://www.ncbi.nlm.nih.gov/pubmed/22711909
http://dx.doi.org/10.1194/jlr.M024471