Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel

[Image: see text] The TRPV4 calcium-permeable cation channel plays important physiological roles in osmosensation, mechanosensation, cell barrier formation, and bone homeostasis. Recent studies reported that mutations in TRPV4, including some in its ankyrin repeat domain (ARD), are associated with h...

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Detalles Bibliográficos
Autores principales: Inada, Hitoshi, Procko, Erik, Sotomayor, Marcos, Gaudet, Rachelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413242/
https://www.ncbi.nlm.nih.gov/pubmed/22702953
http://dx.doi.org/10.1021/bi300279b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413242/
https://www.ncbi.nlm.nih.gov/pubmed/22702953
http://dx.doi.org/10.1021/bi300279b

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