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Performance of computational tools in evaluating the functional impact of laboratory-induced amino acid mutations
Summary: Site-directed mutagenesis is frequently used by scientists to investigate the functional impact of amino acid mutations in the laboratory. Over 10 000 such laboratory-induced mutations have been reported in the UniProt database along with the outcomes of functional assays. Here, we explore...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413386/ https://www.ncbi.nlm.nih.gov/pubmed/22685075 http://dx.doi.org/10.1093/bioinformatics/bts336 |