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Spatial Structure and Lamarckian Adaptation Explain Extreme Genetic Diversity at CRISPR Locus
Even within similar bacterial strains, it has been found that the clustered, regularly interspaced short palindromic repeat (CRISPR) shows a large variability of spacers. Modeling bacterial strains with different levels of immunity to infection by a single virulent phage, we find that coexistence in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413401/ https://www.ncbi.nlm.nih.gov/pubmed/22807565 http://dx.doi.org/10.1128/mBio.00126-12 |