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Virus-mediated swapping of zolpidem-insensitive with zolpidem-sensitive GABA(A) receptors in cortical pyramidal cells

Recently developed pharmacogenetic and optogenetic approaches, with their own advantages and disadvantages, have become indispensable tools in modern neuroscience. Here, we employed a previously described knock-in mouse line (GABA(A)Rγ2(77I)lox) in which the γ2 subunit of the GABA(A) receptor (GABA(...

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Detalles Bibliográficos
Autores principales: Sumegi, Mate, Fukazawa, Yugo, Matsui, Ko, Lorincz, Andrea, Eyre, Mark D, Nusser, Zoltan, Shigemoto, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413495/
https://www.ncbi.nlm.nih.gov/pubmed/22351636
http://dx.doi.org/10.1113/jphysiol.2012.227538