A comparative analysis of protein targets of withdrawn cardiovascular drugs in human and mouse

BACKGROUND: Mouse is widely used in animal testing of cardiovascular disease. However, a large number of cardiovascular drugs that have been experimentally proved to work well on mouse were withdrawn because they caused adverse side effects in human. METHODS: In this study, we investigate whether bi...

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Detalles Bibliográficos
Autores principales: Zhao, Yuqi, Wang, Jingwen, Wang, Yanjie, Huang, Jingfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413526/
https://www.ncbi.nlm.nih.gov/pubmed/22548699
http://dx.doi.org/10.1186/2043-9113-2-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413526/
https://www.ncbi.nlm.nih.gov/pubmed/22548699
http://dx.doi.org/10.1186/2043-9113-2-10

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