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A comparative analysis of protein targets of withdrawn cardiovascular drugs in human and mouse
BACKGROUND: Mouse is widely used in animal testing of cardiovascular disease. However, a large number of cardiovascular drugs that have been experimentally proved to work well on mouse were withdrawn because they caused adverse side effects in human. METHODS: In this study, we investigate whether bi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413526/ https://www.ncbi.nlm.nih.gov/pubmed/22548699 http://dx.doi.org/10.1186/2043-9113-2-10 |