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MMP-13 Regulates Growth of Wound Granulation Tissue and Modulates Gene Expression Signatures Involved in Inflammation, Proteolysis, and Cell Viability

Proteinases play a pivotal role in wound healing by regulating cell-matrix interactions and availability of bioactive molecules. The role of matrix metalloproteinase-13 (MMP-13) in granulation tissue growth was studied in subcutaneously implanted viscose cellulose sponge in MMP-13 knockout (Mmp13 (−...

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Detalles Bibliográficos
Autores principales: Toriseva, Mervi, Laato, Matti, Carpén, Olli, Ruohonen, Suvi T., Savontaus, Eriika, Inada, Masaki, Krane, Stephen M., Kähäri, Veli-Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413640/
https://www.ncbi.nlm.nih.gov/pubmed/22880047
http://dx.doi.org/10.1371/journal.pone.0042596