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MMP-13 Regulates Growth of Wound Granulation Tissue and Modulates Gene Expression Signatures Involved in Inflammation, Proteolysis, and Cell Viability
Proteinases play a pivotal role in wound healing by regulating cell-matrix interactions and availability of bioactive molecules. The role of matrix metalloproteinase-13 (MMP-13) in granulation tissue growth was studied in subcutaneously implanted viscose cellulose sponge in MMP-13 knockout (Mmp13 (−...
Autores principales: | Toriseva, Mervi, Laato, Matti, Carpén, Olli, Ruohonen, Suvi T., Savontaus, Eriika, Inada, Masaki, Krane, Stephen M., Kähäri, Veli-Matti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413640/ https://www.ncbi.nlm.nih.gov/pubmed/22880047 http://dx.doi.org/10.1371/journal.pone.0042596 |
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