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Curcumin Prevents Formation of Polyglutamine Aggregates by Inhibiting Vps36, a Component of the ESCRT-II Complex

Small molecules with antioxidative properties have been implicated in amyloid disorders. Curcumin is the active ingredient present in turmeric and known for several biological and medicinal effects. Adequate evidence substantiates the importance of curcumin in Alzheimer's disease and recent evi...

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Detalles Bibliográficos
Autores principales: Verma, Meenakshi, Sharma, Abhishek, Naidu, Swarna, Bhadra, Ankan Kumar, Kukreti, Ritushree, Taneja, Vibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413662/
https://www.ncbi.nlm.nih.gov/pubmed/22880132
http://dx.doi.org/10.1371/journal.pone.0042923