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Estimating Point and Interval Frequency of Antigen-Specific CD4(+) T Cells Based on Short In Vitro Expansion and Improved Poisson Distribution Analysis
BACKGROUND: Knowledge of antigen-specific CD4(+) T cells frequencies is pivotal to the choice of the antigen to be used in anti-viral and anti-tumor vaccination procedures and for monitoring of immune responses. Methods that employ small cell numbers from patient samples, are easy to perform and do...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413706/ https://www.ncbi.nlm.nih.gov/pubmed/22879946 http://dx.doi.org/10.1371/journal.pone.0042340 |