Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells

Recently, thioridazine (10-[2-(1-methyl-2-piperidyl) ethyl]-2-methylthiophenothiazine), a well-known anti-psychotic agent was found to have anti-cancer activity in cancer cells. However, the molecular mechanism of the agent in cellular signal pathways has not been well defined. Thioridazine signific...

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Detalles Bibliográficos
Autores principales: Kang, Sokbom, Dong, Seung Myung, Kim, Boh-Ram, Park, Mi Sun, Trink, Barry, Byun, Hyun-Jung, Rho, Seung Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413814/
https://www.ncbi.nlm.nih.gov/pubmed/22460505
http://dx.doi.org/10.1007/s10495-012-0717-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413814/
https://www.ncbi.nlm.nih.gov/pubmed/22460505
http://dx.doi.org/10.1007/s10495-012-0717-2

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