Phase 1b dose-finding study of motesanib with docetaxel or paclitaxel in patients with metastatic breast cancer

The purpose of this study was to investigate the safety, tolerability, and pharmacokinetics of motesanib when combined with docetaxel or paclitaxel in patients with metastatic breast cancer. In this open-label, dose-finding, phase 1b study, patients received motesanib 50 or 125-mg orally once daily...

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Detalles Bibliográficos
Autores principales: De Boer, Richard H., Kotasek, Dusan, White, Shane, Koczwara, Bogda, Mainwaring, Paul, Chan, Arlene, Melara, Rebeca, Ye, Yining, Adewoye, Adeboye H., Sikorski, Robert, Kaufman, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413817/
https://www.ncbi.nlm.nih.gov/pubmed/22872523
http://dx.doi.org/10.1007/s10549-012-2135-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413817/
https://www.ncbi.nlm.nih.gov/pubmed/22872523
http://dx.doi.org/10.1007/s10549-012-2135-0

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