Bryostatin-1 vs. TPPB: Dose-Dependent APP Processing and PKC-α, -δ, and -ε Isoform Activation in SH-SY5Y Neuronal Cells

Activation of the α-secretase processing pathway of amyloid precursor protein (APP) is recognized as an important mechanism which diverts APP processing from production of beta-amyloid (Aβ) to non toxic sAPPα, decreasing Alzheimer’s disease (AD) plaque formation and AD-associated cognitive deficits....

Descripción completa

Detalles Bibliográficos
Autores principales: Yi, P., Schrott, L., Castor, T. P., Alexander, J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press Inc 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413820/
https://www.ncbi.nlm.nih.gov/pubmed/22700373
http://dx.doi.org/10.1007/s12031-012-9816-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413820/
https://www.ncbi.nlm.nih.gov/pubmed/22700373
http://dx.doi.org/10.1007/s12031-012-9816-3

Ejemplares similares