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Bryostatin-1 vs. TPPB: Dose-Dependent APP Processing and PKC-α, -δ, and -ε Isoform Activation in SH-SY5Y Neuronal Cells

Activation of the α-secretase processing pathway of amyloid precursor protein (APP) is recognized as an important mechanism which diverts APP processing from production of beta-amyloid (Aβ) to non toxic sAPPα, decreasing Alzheimer’s disease (AD) plaque formation and AD-associated cognitive deficits....

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Detalles Bibliográficos
Autores principales:	Yi, P., Schrott, L., Castor, T. P., Alexander, J. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Humana Press Inc 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413820/ https://www.ncbi.nlm.nih.gov/pubmed/22700373 http://dx.doi.org/10.1007/s12031-012-9816-3

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