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The Protective Effect of Minocycline in a Paraquat-Induced Parkinson's Disease Model in Drosophila is Modified in Altered Genetic Backgrounds

Epidemiological studies link the herbicide paraquat to increased incidence of Parkinson's disease (PD). We previously reported that Drosophila exposed to paraquat recapitulate PD symptoms, including region-specific degeneration of dopaminergic neurons. Minocycline, a tetracycline derivative, ex...

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Detalles Bibliográficos
Autores principales: Inamdar, Arati A., Chaudhuri, Anathbandhu, O'Donnell, Janis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413958/
https://www.ncbi.nlm.nih.gov/pubmed/22900232
http://dx.doi.org/10.1155/2012/938528