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Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms

Physiologically based Pharmacokinetic (PBPK) models are used for predictions of internal or target dose from environmental and pharmacologic chemical exposures. Their use in human risk assessment is dependent on the nature of databases (animal or human) used to develop and test them, and includes ex...

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Detalles Bibliográficos
Autores principales: Caldwell, Jane C., Evans, Marina V., Krishnan, Kannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413973/
https://www.ncbi.nlm.nih.gov/pubmed/22899915
http://dx.doi.org/10.1155/2012/852384