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Protection from Inflammatory Organ Damage in a Murine Model of Hemophagocytic Lymphohistiocytosis Using Treatment with IL-18 Binding Protein

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition due to the association of an infectious agent with lymphocyte cytotoxicity defects, either of congenital genetic origin in children or presumably acquired in adults. In HLH patients, an excess of lymphocyte or macrophage cytoki...

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Detalles Bibliográficos
Autores principales: Chiossone, Laura, Audonnet, Sandra, Chetaille, Bruno, Chasson, Lionel, Farnarier, Catherine, Berda-Haddad, Yael, Jordan, Stefan, Koszinowski, Ulrich H., Dalod, Marc, Mazodier, Karin, Novick, Daniela, Dinarello, Charles A., Vivier, Eric, Kaplanski, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413989/
https://www.ncbi.nlm.nih.gov/pubmed/22891066
http://dx.doi.org/10.3389/fimmu.2012.00239